Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904400 | 0.86 | HTR2C (0.54) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL24109924 | 0.86 | HTR2C (0.54) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL18997057 | 0.82 | HTR2C (0.59) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL24110213 | 0.80 | HTR2C (0.60) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL7962397 | 0.76 | HTR2C (0.59) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL24109929 | 0.76 | HTR2C (0.62) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL25523389 | 0.75 | HTR2C (0.42) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL25521898 | 0.75 | HTR2C (0.42) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL24110371 | 0.74 | HTR2C (0.50) | HTR2CHTR2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL7232114 | 0.74 | HTR2C (0.64) | HTR2CHTR2AMTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159456-A1 | N-SUBSTITUTED INDOLES | TERRAN BIOSCIENCES INC (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159456-A1 | N-SUBSTITUTED INDOLES | TPH2, TPH1, AANAT | HTR2C 11/4885HTR2A 13/4885MTNR1A 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.