Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814819 | 1.00 | HPGD (0.65) | HPGDALDH1A1MAPTGLAKMT2A | |
| SCHEMBL2377995 | 0.86 | HRH3 (0.61) | HPGDKMT2ALMNAHRH3MEN1 | |
| SCHEMBL23775255 | 0.84 | ALDH1A1 (0.58) | HPGDALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL1007945 | 0.82 | HPGD (0.61) | HPGDALDH1A1MAPTGLAKMT2A | |
| SCHEMBL17790202 | 0.82 | HPGD (0.60) | HPGDALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL21321950 | 0.81 | HPGD (0.71) | HPGDALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL7901274 | 0.81 | HPGD (0.71) | HPGDALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL3814813 | 0.81 | HPGD (0.61) | HPGDALDH1A1MAPTGLAKMT2A | |
| SCHEMBL21015837 | 0.81 | ALDH1A1 (0.58) | HPGDALDH1A1MAPTGLAKMT2A | |
| SCHEMBL7132525 | 0.80 | HPGD (1.00) | HPGDALDH1A1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | ALKBH1, ALKBH5, ALKBH3 | HPGD 4839/4885ALDH1A1 1427/4885MAPT 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.