Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 6/20 | 0.32 |
| ▸ | JAK1 | P23458 | 6/20 | 0.32 |
| ▸ | TYK2 | P29597 | 6/20 | 0.32 |
| ▸ | KDR | P35968 | 6/20 | 0.32 |
| ▸ | JAK3 | P52333 | 6/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.32 |
| ▸ | VRK1 | Q99986 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523362 | 0.87 | VRK1 (0.35) | KDM4EJAK2JAK1TYK2KDR | |
| SCHEMBL25524102 | 0.77 | ABCG2 (0.47) | KDM4EPARP1 | |
| SCHEMBL25521795 | 0.77 | KDM4E (0.48) | KDM4E | |
| SCHEMBL25526984 | 0.74 | HRH4 (0.36) | — | |
| SCHEMBL25522043 | 0.72 | VRK1 (0.36) | VRK1 | |
| SCHEMBL25523902 | 0.71 | TNIK (0.45) | — | |
| SCHEMBL25522055 | 0.71 | VRK1 (0.35) | JAK2JAK1TYK2KDRJAK3 | |
| SCHEMBL25521932 | 0.70 | KDM4E (0.49) | KDM4EPARP1 | |
| SCHEMBL25522052 | 0.69 | ABL1 (0.44) | — | |
| SCHEMBL25524104 | 0.68 | PDGFRB (0.51) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |