Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25520063 | 0.87 | KDM4E (0.46) | KDM4EPARP1HSD17B1HSD17B2NR1H2 | |
| SCHEMBL25522210 | 0.83 | KDM4E (0.42) | KDM4EPARP1HSD17B1HSD17B2NR1H2 | |
| SCHEMBL25524102 | 0.76 | ABCG2 (0.47) | KDM4EPARP1ESR1 | |
| SCHEMBL25521795 | 0.76 | KDM4E (0.48) | KDM4EL3MBTL1 | |
| SCHEMBL25524104 | 0.75 | PDGFRB (0.51) | KDM4EAKR1C3AKR1C2 | |
| SCHEMBL23717257 | 0.75 | PSMD14 (0.42) | KDM4EPARP1NR1H2NR1H3AKR1C3 | |
| SCHEMBL25521794 | 0.73 | KDM4E (0.39) | KDM4EPARP1HSD17B1HSD17B2L3MBTL1 | |
| SCHEMBL25764079 | 0.72 | ESR1 (0.39) | NR1H2NR1H3AKR1C3AKR1C2HSD11B1 | |
| SCHEMBL25763766 | 0.71 | CYP11B2 (0.52) | NR1H2NR1H3 | |
| SCHEMBL25522191 | 0.71 | NPC1 (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |