Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 5/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523414 | 0.84 | KDM4E (0.51) | KDM4EL3MBTL1RAB9ANPC1MET | |
| SCHEMBL25522331 | 0.83 | L3MBTL1 (0.50) | KDM4EL3MBTL1RAB9ANPC1MET | |
| SCHEMBL25521931 | 0.83 | DYRK1A (0.46) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25522043 | 0.81 | VRK1 (0.36) | ADORA1 | |
| SCHEMBL25523955 | 0.79 | KDM4E (0.43) | KDM4EL3MBTL1RAB9ANPC1MMP2 | |
| SCHEMBL25523903 | 0.78 | KDM4E (0.40) | KDM4EL3MBTL1NPC1COMT | |
| SCHEMBL25524101 | 0.78 | MMP2 (0.45) | KDM4EL3MBTL1RAB9ANPC1RAD52 | |
| SCHEMBL25524102 | 0.78 | ABCG2 (0.47) | KDM4E | |
| SCHEMBL25522050 | 0.78 | RPS6KA3 (0.41) | KDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL25523838 | 0.77 | KDM4E (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |