Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523416 | 0.86 | PDGFRB (0.43) | TNIKPDGFRBPDGFRAEGFRMET | |
| SCHEMBL25524010 | 0.83 | CYP1A2 (0.41) | TNIKPDGFRBPDGFRAEGFRMAP4K4 | |
| SCHEMBL25521798 | 0.83 | MAOB (0.41) | GCGRMAP4K4ESR2 | |
| SCHEMBL25524104 | 0.82 | PDGFRB (0.51) | PDGFRBPDGFRAMETMAP4K4CLK4 | |
| SCHEMBL25524012 | 0.81 | CYP11B1 (0.38) | PDGFRBPDGFRAEGFRMET | |
| SCHEMBL25521800 | 0.76 | AAK1 (0.47) | ACVR1 | |
| SCHEMBL25524102 | 0.75 | ABCG2 (0.47) | PDGFRBPDGFRAGCGRGRIN2BESR2 | |
| SCHEMBL25520070 | 0.75 | MEN1 (0.40) | — | |
| SCHEMBL25522057 | 0.74 | TGFBR1 (0.40) | EGFR | |
| SCHEMBL25524007 | 0.74 | PDGFRB (0.40) | PDGFRBPDGFRAEGFRMAP4K4CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |