Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523542 | 0.87 | EGLN1 (0.37) | CYP11B1CYP11B2PARP1HPGDSCYP17A1 | |
| SCHEMBL25523902 | 0.81 | TNIK (0.45) | PDGFRBPDGFRAEGFRMET | |
| SCHEMBL25524010 | 0.79 | CYP1A2 (0.41) | PDGFRBPDGFRAEGLN1EGFRFLT1 | |
| SCHEMBL25524104 | 0.78 | PDGFRB (0.51) | PDGFRBPDGFRAPIK3CAMET | |
| SCHEMBL15481082 | 0.74 | HPGDS (0.38) | HPGDSEGLN1 | |
| SCHEMBL25524046 | 0.72 | TGFBR1 (0.44) | CYP11B1CYP11B2EGFRPIK3CAPRKDC | |
| SCHEMBL25524007 | 0.70 | PDGFRB (0.40) | PDGFRBPDGFRAEGFRPIK3CAPIK3CB | |
| SCHEMBL25522057 | 0.70 | TGFBR1 (0.40) | EGLN1EGFRFLT1PIK3CAPIK3CB | |
| SCHEMBL16289110 | 0.70 | CYP1A2 (0.52) | CYP11B1CYP11B2HPGDSPIK3CAGSK3B | |
| SCHEMBL25522041 | 0.69 | AKR1C3 (0.35) | PDGFRBPDGFRAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086428-A2 | NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |