Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25524789 | 0.87 | GPR119 (0.37) | GPR119HTTMAPK1USP2SMN1; SMN2 | |
| SCHEMBL25684889 | 0.85 | GPR119 (0.37) | GPR119HTTMAPK1USP2SMN1; SMN2 | |
| SCHEMBL25524072 | 0.83 | USP2 (0.43) | GPR119HTTMAPK1USP2SMN1; SMN2 | |
| SCHEMBL22994977 | 0.76 | USP2 (0.46) | GPR119HTTMAPK1USP2SMN1; SMN2 | |
| SCHEMBL24670979 | 0.76 | USP2 (0.49) | HTTMAPK1USP2SMN1; SMN2NPC1 | |
| SCHEMBL4379500 | 0.74 | USP2 (0.50) | HTTUSP2SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL25524991 | 0.74 | USP2 (0.46) | HTTMAPK1USP2SMN1; SMN2NPC1 | |
| SCHEMBL4391742 | 0.73 | USP2 (0.49) | GPR119HTTMAPK1USP2SMN1; SMN2 | |
| SCHEMBL25524385 | 0.73 | EPHX2 (0.39) | GPR119HTTMAPK1USP2SMN1; SMN2 | |
| SCHEMBL3565907 | 0.73 | USP2 (0.51) | HTTMAPK1USP2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078946-A1 | LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY | ZIPHIUS VACCINES NV (BE) | 2023-05-11 | — | — | WO | disclosed |