Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.35 |
| ▸ | OXTR | P30559 | 4/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2552411 | 0.85 | AVPR1A (0.34) | AVPR1ATACR1KCNH2 | |
| SCHEMBL2564864 | 0.85 | AVPR2 (0.37) | AVPR2OXTRAVPR1AKCNH2 | |
| SCHEMBL2556524 | 0.82 | CYP11B2 (0.32) | AVPR2AVPR1AKCNH2 | |
| SCHEMBL2550063 | 0.81 | NAMPT (0.40) | AVPR2OXTRAVPR1ATACR1KCNH2 | |
| SCHEMBL2565565 | 0.81 | AVPR1A (0.32) | AVPR2OXTRAVPR1AKCNH2 | |
| SCHEMBL2564697 | 0.81 | AVPR1A (0.31) | AVPR2AVPR1AKCNH2 | |
| SCHEMBL2564173 | 0.81 | AVPR2 (0.31) | AVPR2 | |
| SCHEMBL2347000 | 0.81 | AVPR2 (0.31) | AVPR2OXTRAVPR1A | |
| Hydrochloric Acid SCHEMBL2544777 | 0.80 | AVPR1A (0.33) | AVPR1A | |
| SCHEMBL2549332 | 0.76 | AVPR1A (0.37) | AVPR2OXTRAVPR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552919-A1 | ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F. Hoffmann-La Roche AG (CH) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011120877-A1 | ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-10-06 | — | — | WO | disclosed |