Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.42 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | IL1B | P01584 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959034 | 0.87 | CRBN (0.46) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL25671252 | 0.86 | CRBN (0.47) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL21311550 | 0.84 | CRBN (0.49) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL23418261 | 0.84 | CRBN (0.41) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL28602539 | 0.82 | CRBN (0.45) | CRBNBRD4MAP1LC3B | |
| SCHEMBL21480839 | 0.81 | CRBN (0.62) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL27097876 | 0.81 | CRBN (0.62) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL22733298 | 0.81 | CRBN (0.49) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL20652629 | 0.81 | HTR2B (0.53) | CRBNBRD4IKZF3IKZF1TNF | |
| SCHEMBL23319245 | 0.81 | CRBN (0.47) | CRBNBRD4IKZF3IKZF1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078813-A1 | HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |