Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379369 | 0.86 | MCL1 (0.52) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL12108 | 0.84 | ALOX5 (0.46) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL13712773 | 0.83 | MAOA (0.51) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL1324122 | 0.82 | PTGS2 (0.57) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL29398254 | 0.82 | PTGS2 (0.57) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL13005222 | 0.81 | MAOA (0.64) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL12608741 | 0.81 | MAOA (0.68) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL7253352 | 0.81 | TTR (0.67) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL29838129 | 0.81 | TTR (0.67) | MAOAKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL24120562 | 0.80 | PTGS2 (0.71) | MAOAKDM4EALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278176-B1 | Compounds having antitumour and antibacterial properties | WARNER LAMBERT CO (US) | 1994-03-09 | — | — | EP | claimed |
| EP-0278176-A2 | Compounds having antitumour and antibacterial properties | WARNER-LAMBERT COMPANY (US) | 1988-08-17 | — | — | EP | claimed |
| WO-2021215943-A1 | XANTHONE DERIVATIVES, UV PROTECTIVE COMPOSITION CONCENTRATE, METHOD OF PREPARATION OF UV PROTECTIVE COMPOSITION CONCENTRATE, USE OF UV PROTECTIVE COMPOSITION CONCENTRATE AND COSMETIC UV PROTECTIVE PRODUCT | UNIWERSYTET JAGIELLONSKI (PL) | 2021-10-28 | — | — | WO | disclosed |
| US-20210336155-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2021-10-28 | — | — | US | disclosed |
| WO-2019228430-A1 | KETONE-CONTAINING COMPOUND AND USE THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE | 江苏三月光电科技有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| US-9163002-B2 | Methodology for the synthesis of xanthones | UNIVERSITY OF SOUTH CAROLINA (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | UNIVERSITY OF SOUTH CAROLINA | 2014-04-17 | — | — | US | disclosed |
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |
| EP-0278176-B1 | Compounds having antitumour and antibacterial properties | WARNER LAMBERT CO (US) | 1994-03-09 | — | — | EP | disclosed |
| US-5281620-A | Alkyl substituted xanthenone-4-acetic acid | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0278176-A2 | Compounds having antitumour and antibacterial properties | WARNER-LAMBERT COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | XDH, TYR, NISCH | MAOA 68/4885KDM4E 1101/4885ALDH1A1 857/4885 |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | MAOA 403/4885KDM4E 4342/4885ALDH1A1 151/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | MAOA 403/4885KDM4E 4342/4885ALDH1A1 151/4885 |
| US-20210336155-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | CCNL2, MCM6, CRY1 | MAOA 1754/4885KDM4E 2468/4885ALDH1A1 2007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.