SCHEMBL25524965

SCHEMBL25524965

CC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 1/20 0.44
▸ NAA50 Q9GZZ1 1/20 0.42
▸ STAT3 P40763 1/20 0.38
▸ CTSD P07339 1/20 0.38
▸ CTSE P14091 1/20 0.38
▸ KEAP1 Q14145 3/20 0.38
▸ RAMP3 O60896 4/20 0.37
▸ CALCR P30988 4/20 0.37
▸ NMUR2 Q9GZQ4 1/20 0.37
▸ NMUR1 Q9HB89 1/20 0.37
▸ PSMB9 P28065 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018383 0.95 NAA50 (0.44) APLNRNAA50CTSDCTSERAMP3
SCHEMBL22018529 0.95 NAA50 (0.44) APLNRNAA50RAMP3CALCRNMUR2
SCHEMBL22380817 0.93 NAA50 (0.42) APLNRNAA50CTSDCTSERAMP3
SCHEMBL29308413 0.93 NAA50 (0.42) APLNRNAA50CTSDCTSERAMP3
SCHEMBL29308423 0.93 NAA50 (0.42) APLNRNAA50CTSDCTSERAMP3
SCHEMBL22018812 0.93 NAA50 (0.42) APLNRNAA50CTSDCTSERAMP3
SCHEMBL22018310 0.93 NAA50 (0.42) APLNRNAA50CTSDCTSERAMP3
SCHEMBL23871318 0.93 NAA50 (0.48) APLNRNAA50CTSDCTSERAMP3
SCHEMBL25524969 0.93 KEAP1 (0.43) APLNRNAA50KEAP1RAMP3CALCR
SCHEMBL29308396 0.93 RAMP3 (0.43) APLNRNAA50RAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP APLNR 90/4885NAA50 3485/4885STAT3 684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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