Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12845100 | 0.88 | HRH4 (0.55) | RAB9AL3MBTL1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL21843807 | 0.84 | MAPT (0.52) | RAB9AKMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL12845203 | 0.80 | RAB9A (0.57) | RAB9AL3MBTL1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL14824927 | 0.78 | RAB9A (0.56) | RAB9AL3MBTL1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL13761492 | 0.76 | RAB9A (0.53) | RAB9AL3MBTL1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL12845127 | 0.76 | RAB9A (0.53) | RAB9AL3MBTL1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL11833547 | 0.76 | RAB9A (0.53) | RAB9AL3MBTL1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL1619421 | 0.75 | RAB9A (0.52) | RAB9AL3MBTL1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL29883723 | 0.73 | L3MBTL1 (0.52) | RAB9AL3MBTL1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL10127337 | 0.73 | HTR3A (0.49) | RAB9AL3MBTL1HRH4HTR3APANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | RAB9A 880/4885L3MBTL1 2548/4885KMT2A 1605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.