Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | WNT1 | P04628 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25527226 | 1.00 | HPGD (0.56) | HPGDADORA3SMN1; SMN2MAPK8MAPK10 | |
| SCHEMBL19439103 | 0.85 | HPGD (0.77) | HPGDADORA3SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL30052336 | 0.78 | CTSC (0.44) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30052457 | 0.78 | CTSC (0.44) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23885156 | 0.78 | CTSC (0.44) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23885677 | 0.78 | CTSC (0.44) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30052549 | 0.78 | CTSC (0.44) | HPGDSMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23885158 | 0.75 | CFD (0.48) | SLC6A2SLC6A4SLC6A3CFD | |
| SCHEMBL1464415 | 0.74 | HPGD (0.58) | HPGDADORA3SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL23089299 | 0.72 | HPGD (0.46) | HPGDADORA3SMN1; SMN2MAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | C5, C9, C1QBP | HPGD 808/4885ADORA3 1388/4885SMN1; SMN2 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.