Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617989 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL6620402 | 0.79 | NPC1 (0.43) | MEN1KMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL10811677 | 0.78 | AHR (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1904655 | 0.77 | QPCT (0.39) | KDM4EMEN1KMT2AALDH1A1PRKDC | |
| SCHEMBL15584575 | 0.76 | PPARG (0.51) | ALDH1A1L3MBTL1MAPTNTRK1TDP1 | |
| SCHEMBL17034341 | 0.76 | KMT2A (0.46) | KDM4EMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL4791279 | 0.75 | MAPT (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13736042 | 0.75 | NUDT1 (0.39) | KDM4EKMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL1168107 | 0.75 | MEN1 (0.38) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8580981 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |