Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 16/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528617 | 0.91 | ROCK2 (0.35) | ROCK2ROCK1F10KCNH2CACNA1I | |
| SCHEMBL25528747 | 0.91 | MAPK14 (0.38) | ROCK2ROCK1F10KCNH2CACNA1I | |
| SCHEMBL25528189 | 0.89 | ROCK2 (0.40) | ROCK2ROCK1 | |
| SCHEMBL25530084 | 0.88 | ROCK2 (0.41) | ROCK2ROCK1 | |
| SCHEMBL25528921 | 0.88 | ROCK2 (0.41) | ROCK2ROCK1 | |
| SCHEMBL25528619 | 0.87 | ROCK2 (0.40) | ROCK2ROCK1 | |
| SCHEMBL25532226 | 0.87 | ROCK2 (0.43) | ROCK2ROCK1F10 | |
| SCHEMBL25529068 | 0.86 | ROCK2 (0.43) | ROCK2ROCK1 | |
| SCHEMBL25528185 | 0.86 | ROCK2 (0.43) | ROCK2ROCK1 | |
| SCHEMBL25528194 | 0.85 | ROCK2 (0.39) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |