Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 15/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25532225 | 0.94 | ROCK2 (0.40) | ROCK2ROCK1CACNA1G | |
| SCHEMBL25532515 | 0.91 | ROCK2 (0.33) | ROCK2ROCK1 | |
| SCHEMBL25528479 | 0.91 | CACNA1H (0.33) | ROCK2ROCK1 | |
| SCHEMBL25529070 | 0.91 | CACNA1H (0.33) | ROCK2ROCK1 | |
| SCHEMBL25528346 | 0.90 | ROCK2 (0.36) | ROCK2ROCK1CACNA1GKDM4E | |
| SCHEMBL25528619 | 0.89 | ROCK2 (0.40) | ROCK2ROCK1 | |
| SCHEMBL25528480 | 0.89 | ROCK2 (0.43) | ROCK2ROCK1 | |
| SCHEMBL25528921 | 0.87 | ROCK2 (0.41) | ROCK2ROCK1 | |
| SCHEMBL25530084 | 0.87 | ROCK2 (0.41) | ROCK2ROCK1 | |
| SCHEMBL25528474 | 0.86 | ROCK2 (0.41) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |