Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.48 |
| ▸ | THRB | P10828 | 8/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23003609 | 0.92 | THRA (0.59) | THRATHRBALOX5CNR1CNR2 | |
| SCHEMBL25528524 | 0.92 | THRA (0.51) | THRATHRBFFAR1PLA2G10PLA2G2A | |
| SCHEMBL25528534 | 0.90 | THRA (0.50) | THRATHRBFFAR1PLA2G10PLA2G2A | |
| SCHEMBL25528542 | 0.88 | THRA (0.48) | THRATHRBFFAR1PLA2G10PLA2G2A | |
| SCHEMBL23003761 | 0.88 | THRA (0.45) | THRATHRBALOX5CNR1CNR2 | |
| SCHEMBL25528562 | 0.88 | THRA (0.52) | THRATHRBALOX5PLA2G10PLA2G2A | |
| SCHEMBL25528603 | 0.87 | THRB (0.49) | THRATHRBFFAR1PLA2G10PLA2G2A | |
| SCHEMBL25528523 | 0.87 | THRA (0.51) | THRATHRBFFAR1PLA2G10PLA2G2A | |
| SCHEMBL25528706 | 0.86 | THRA (0.57) | THRATHRBFFAR1PLA2G10PLA2G2A | |
| SCHEMBL23003817 | 0.86 | THRA (0.43) | THRATHRBALOX5MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667606-B2 | Thyromimetics | TPO, TSHR, TTR | THRA 4/4885THRB 9/4885ALOX5 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.