SCHEMBL25528626 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CCR3	P51677	2/20	0.37

▸	ROCK2	O75116	7/20	0.36

▸	ROCK1	Q13464	6/20	0.36

▸	MAP4K4	O95819	1/20	0.34

▸	BRD4	O60885	4/20	0.34

▸	AURKA	O14965	1/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	CYP2D6	P10635	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25531283	0.90	CACNA1H (0.36)	ROCK2ROCK1MAP4K4AURKA
SCHEMBL25528475	0.90	CACNA1H (0.36)	ROCK2ROCK1MAP4K4AURKA
SCHEMBL25530204	0.86	ROCK1 (0.35)	CCR3ROCK2ROCK1
SCHEMBL25528470	0.86	AURKA (0.37)	ROCK2ROCK1MAP4K4AURKA
SCHEMBL25528473	0.83	AURKA (0.35)	ROCK2ROCK1BRD4AURKA
SCHEMBL25528948	0.81	ROCK2 (0.33)	ROCK2ROCK1AURKA
SCHEMBL25528945	0.81	CACNA1H (0.36)	ROCK2ROCK1AURKA
SCHEMBL25531296	0.81	ROCK2 (0.33)	ROCK2ROCK1AURKA
SCHEMBL25531302	0.78	ROCK2 (0.41)	ROCK2ROCK1BRD4
SCHEMBL25529501	0.77	ROCK1 (0.47)	ROCK2ROCK1BRD4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023093787-A1	BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR	成都奥睿药业有限公司	2023-06-01	—	—	WO	disclosed