Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528479 | 0.94 | CACNA1H (0.33) | F10ROCK2MAPK14ROCK1BRD4 | |
| SCHEMBL25529070 | 0.94 | CACNA1H (0.33) | F10ROCK2MAPK14ROCK1BRD4 | |
| SCHEMBL25532225 | 0.92 | ROCK2 (0.40) | ROCK2ROCK1 | |
| SCHEMBL25532515 | 0.87 | ROCK2 (0.33) | ROCK2ROCK1BRD4 | |
| SCHEMBL25528924 | 0.86 | CACNA1H (0.37) | F10ROCK2ROCK1GAA | |
| SCHEMBL25528750 | 0.86 | ROCK2 (0.33) | ROCK2ROCK1BRD4 | |
| SCHEMBL25528189 | 0.86 | ROCK2 (0.40) | ROCK2ROCK1 | |
| SCHEMBL25528470 | 0.86 | AURKA (0.37) | ROCK2MAPK14ROCK1CYP2C9 | |
| SCHEMBL25528831 | 0.85 | HTR7 (0.36) | F10ROCK2MAPK14ROCK1BRD4 | |
| SCHEMBL25532600 | 0.85 | CACNA1H (0.33) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |