Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528927 | 0.89 | ADORA2A (0.55) | ADORA2AADORA1ADORA2BADORA3PTGS2 | |
| SCHEMBL25243607 | 0.77 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL20600496 | 0.75 | ADORA2A (0.55) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL25528882 | 0.74 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL25528877 | 0.74 | ADORA2A (0.45) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL25528899 | 0.74 | TGFBR1 (0.43) | — | |
| SCHEMBL25528885 | 0.73 | ADORA2A (0.44) | ADORA2AADORA1ADORA2B | |
| SCHEMBL25528890 | 0.73 | MAPK14 (0.47) | ADORA2AADORA1ADORA2B | |
| SCHEMBL25259255 | 0.72 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL30721839 | 0.71 | ADORA2A (0.57) | ADORA2AADORA1ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091604-A1 | ADENOSINE RECEPTOR ANTAGONISTS | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |