Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25536924 | 0.82 | KDM4E (0.40) | TYRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL25529111 | 0.78 | KDM4E (0.44) | TYRALDH1A1KDM4EGAAHPGD | |
| SCHEMBL25529270 | 0.68 | KDM4E (0.35) | KDM4EHSD17B10GAATSHR | |
| SCHEMBL11389408 | 0.67 | ALDH1A1 (0.45) | ALDH1A1MMP1MMP7MMP9MMP8 | |
| SCHEMBL29868078 | 0.66 | MAPT (0.38) | TYRALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL29868349 | 0.66 | ALDH1A1 (0.33) | TYRALDH1A1KDM4EGAAPOLB | |
| SCHEMBL2280549 | 0.66 | L3MBTL1 (0.54) | ALDH1A1KDM4EGAAHPGDTSHR | |
| SCHEMBL7554482 | 0.66 | MMP1 (0.40) | TYRKDM4EMMP1MMP7MMP9 | |
| SCHEMBL23732184 | 0.66 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL23147400 | 0.65 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | PRKACB, PRKACA, PRKX | TYR 1198/4885ALDH1A1 3998/4885KDM4E 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.