Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174175 | 0.89 | L3MBTL1 (0.41) | L3MBTL1TDP1POLBCTDSP1ALDH1A1 | |
| SCHEMBL25529106 | 0.87 | L3MBTL1 (0.44) | L3MBTL1TDP1POLBCTDSP1ALDH1A1 | |
| SCHEMBL30174300 | 0.76 | L3MBTL1 (0.39) | L3MBTL1TDP1POLBCTDSP1ALDH1A1 | |
| SCHEMBL1127114 | 0.73 | L3MBTL1 (0.44) | L3MBTL1TDP1POLBCTDSP1ALDH1A1 | |
| SCHEMBL10462317 | 0.72 | MAP3K14 (0.40) | POLBMEN1KMT2A | |
| SCHEMBL25529268 | 0.69 | USP2 (0.34) | L3MBTL1TSHRUSP2MAPTMEN1 | |
| SCHEMBL25529258 | 0.69 | L3MBTL1 (0.36) | L3MBTL1TDP1POLBCTDSP1ALDH1A1 | |
| SCHEMBL10460355 | 0.66 | TSHR (0.47) | L3MBTL1TDP1POLBALDH1A1RAB9A | |
| SCHEMBL23488197 | 0.66 | L3MBTL1 (0.61) | L3MBTL1TDP1POLBALDH1A1RAB9A | |
| SCHEMBL15162320 | 0.66 | HSP90AA1 (0.47) | L3MBTL1TDP1POLBCTDSP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2023-05-18 | — | — | US | disclosed |
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | EXELIXIS INC (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151003-A1 | COMPOUNDS AND METHODS OF USE | PRKACB, PRKACA, PRKX | L3MBTL1 3091/4885TDP1 612/4885POLB 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.