SCHEMBL23488197

SCHEMBL23488197

CCOC(=O)c1c(-c2ccco2)c(C(=O)OCC)n(C)c1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.61
ALDH1A1 P00352 6/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
KMT2A Q03164 3/20 0.54
PKM P14618 1/20 0.52
HSD17B10 Q99714 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 1/20 0.50
ALOX15 P16050 1/20 0.50
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
ADORA2B P29275 2/20 0.48
USP2 O75604 1/20 0.48
TSHR P16473 2/20 0.47
MAPT P10636 2/20 0.47
ABL1 P00519 1/20 0.47
F2 P00734 1/20 0.47
HPGD P15428 1/20 0.47
RIN1 Q13671 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15162320 0.80 HSP90AA1 (0.47) L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A
SCHEMBL1127045 0.79 TSHR (0.68) ALDH1A1CYP1A2CYP2C19KMT2ATDP1
SCHEMBL15151391 0.76 ALDH1A1 (0.72) L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A
SCHEMBL1991026 0.74 ALDH1A1 (0.56) ALDH1A1KMT2AHSD17B10TDP1MEN1
SCHEMBL23488205 0.73 L3MBTL1 (0.66) L3MBTL1ALDH1A1KMT2APKMHSD17B10
SCHEMBL11363402 0.71 KMT2A (1.00) L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A
SCHEMBL257221 0.69 KMT2A (0.69) L3MBTL1ALDH1A1CYP1A2CYP2C19KMT2A
SCHEMBL21484965 0.69 TSHR (0.55) ALDH1A1CYP1A2CYP2C19KMT2AHSD17B10
SCHEMBL25529106 0.69 L3MBTL1 (0.44) L3MBTL1ALDH1A1KMT2APKMHSD17B10
SCHEMBL28816299 0.68 ALDH1A1 (0.57) L3MBTL1ALDH1A1KMT2APKMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110010-A1 NOVEL PYRROLE COMPOUND 微境生物医药科技(上海)有限公司 2021-06-10 WO disclosed