SCHEMBL1127114

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15162320	0.88	HSP90AA1 (0.47)	L3MBTL1POLBCTDSP1TDP1ALDH1A1
	SCHEMBL25529106	0.82	L3MBTL1 (0.44)	L3MBTL1POLBCTDSP1TDP1ALDH1A1
	SCHEMBL23488197	0.77	L3MBTL1 (0.61)	L3MBTL1POLBTDP1ALDH1A1RAB9A
	SCHEMBL1127287	0.76	GRIA4 (0.60)	GRIA2GRIA4TSHRUSP2CYP1A2
	SCHEMBL1030274	0.75	POLB (0.46)	L3MBTL1POLBCTDSP1TDP1ALDH1A1
	SCHEMBL1127410	0.73	L3MBTL1 (0.44)	L3MBTL1POLBCTDSP1TDP1ALDH1A1
	SCHEMBL25529288	0.73	L3MBTL1 (0.41)	L3MBTL1POLBCTDSP1TDP1ALDH1A1
	SCHEMBL30174300	0.71	L3MBTL1 (0.39)	L3MBTL1POLBCTDSP1TDP1ALDH1A1
	SCHEMBL1990961	0.71	ERCC1 (0.45)	POLBALDH1A1RAB9AGRIA2GRIA4
	SCHEMBL26597135	0.71	GRIA2 (0.46)	GRIA2GRIA4TSHRUSP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.