Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.30 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530203 | 1.00 | HRH3 (0.38) | HRH3CYP2D6KCNH2FKBP1AMMP2 | |
| SCHEMBL25530199 | 1.00 | HRH3 (0.38) | HRH3CYP2D6KCNH2FKBP1AMMP2 | |
| SCHEMBL24352600 | 0.82 | HRH3 (0.38) | HRH3CYP2D6KCNH2SIGMAR1 | |
| SCHEMBL25530195 | 0.82 | HRH3 (0.38) | HRH3CYP2D6KCNH2SIGMAR1 | |
| SCHEMBL25530196 | 0.82 | HRH3 (0.38) | HRH3CYP2D6KCNH2SIGMAR1 | |
| SCHEMBL17886939 | 0.81 | HRH3 (0.36) | HRH3CYP2D6KCNH2SIGMAR1 | |
| SCHEMBL21795002 | 0.79 | MMP2 (0.36) | HRH3CYP2D6KCNH2MMP2ANPEP | |
| SCHEMBL24448611 | 0.79 | MMP2 (0.36) | HRH3CYP2D6KCNH2MMP2ANPEP | |
| SCHEMBL20314931 | 0.79 | MMP2 (0.36) | HRH3CYP2D6KCNH2MMP2ANPEP | |
| SCHEMBL25533061 | 0.79 | MMP2 (0.36) | HRH3CYP2D6KCNH2MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | HRH3 2165/4885CYP2D6 1521/4885KCNH2 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.