Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 7/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 9/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530256 | 0.90 | MAPK3 (0.42) | ULK1MAPK3PTK2ULK2PIK3C3 | |
| SCHEMBL25209416 | 0.73 | GRM5 (0.38) | ULK1MAPK3PTK2MAPK1 | |
| SCHEMBL30397703 | 0.73 | GRM5 (0.38) | ULK1MAPK3PTK2MAPK1 | |
| SCHEMBL25530170 | 0.71 | ULK1 (0.49) | ULK1MAPK3PTK2PIK3C3 | |
| SCHEMBL25526333 | 0.69 | ULK1 (0.48) | ULK1MAPK3PTK2PIK3C3 | |
| SCHEMBL25531917 | 0.65 | ULK1 (0.46) | ULK1MAPK3PTK2ULK2PIK3C3 | |
| SCHEMBL25532521 | 0.64 | CCNK (0.51) | ULK1MAPK3PTK2PIK3C3 | |
| SCHEMBL21184490 | 0.59 | ULK1 (0.63) | ULK1PTK2ULK2 | |
| SCHEMBL25516292 | 0.59 | ULK1 (0.38) | ULK1ULK2PIK3C3 | |
| SCHEMBL30397931 | 0.58 | CDK2 (0.41) | ULK1MAPK3PTK2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |