Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ESRRG | P62508 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891086 | 0.81 | KCNH2 (0.55) | KCNH2ESRRGLMNASIGMAR1GRIA4 | |
| SCHEMBL13966087 | 0.81 | KCNH2 (0.42) | KCNH2LMNASIGMAR1TP53TSHR | |
| SCHEMBL19122050 | 0.81 | AOC3 (0.55) | KCNH2SIGMAR1ADRA2AADRA1A | |
| SCHEMBL12891007 | 0.79 | KCNH2 (0.58) | KCNH2ESRRGLMNASIGMAR1GRIA4 | |
| SCHEMBL25530538 | 0.77 | KCNH2 (0.59) | KCNH2ESRRGLMNASIGMAR1GRIA4 | |
| SCHEMBL797701 | 0.76 | KCNH2 (0.75) | KCNH2ESRRGLMNASIGMAR1GRIA4 | |
| SCHEMBL25532732 | 0.75 | KCNH2 (0.49) | KCNH2ESRRGLMNASIGMAR1GRIA4 | |
| SCHEMBL7456580 | 0.75 | KCNH2 (0.59) | KCNH2ESRRGLMNASIGMAR1GRIA4 | |
| Bromide SCHEMBL13275917 | 0.75 | KCNH2 (0.72) | KCNH2ESRRGLMNASIGMAR1GRIA4 | |
| SCHEMBL25530556 | 0.74 | KCNH2 (0.43) | KCNH2ESRRGLMNASIGMAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | KCNH2 1953/4885ESRRG 3236/4885LMNA 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.