Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ESRRG | P62508 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12891086 | 0.89 | KCNH2 (0.55) | KCNH2ESRRGLMNASIGMAR1SLC6A4 | |
| SCHEMBL18138032 | 0.82 | OPRM1 (0.56) | KCNH2LMNASLC6A4SLC6A3CHRM2 | |
| SCHEMBL25530527 | 0.82 | HRH3 (0.48) | KCNH2LMNATP53TSHRSIGMAR1 | |
| SCHEMBL25532733 | 0.79 | KCNH2 (0.56) | KCNH2ESRRGLMNASIGMAR1SLC6A4 | |
| SCHEMBL12891007 | 0.77 | KCNH2 (0.58) | KCNH2ESRRGLMNASIGMAR1SLC6A4 | |
| SCHEMBL25530539 | 0.75 | KCNH2 (0.51) | KCNH2ESRRGLMNATP53TSHR | |
| SCHEMBL11133065 | 0.74 | KCNH2 (0.52) | KCNH2TSHRSIGMAR1SLC6A4SLC6A3 | |
| SCHEMBL12203514 | 0.74 | HRH3 (0.61) | KCNH2LMNATSHRSIGMAR1SLC6A4 | |
| SCHEMBL797701 | 0.74 | KCNH2 (0.75) | KCNH2ESRRGLMNASIGMAR1GRIA4 | |
| SCHEMBL7456580 | 0.72 | KCNH2 (0.59) | KCNH2ESRRGLMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | KCNH2 1953/4885ESRRG 3236/4885LMNA 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.