Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21654088 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP2C19RIPK1EPHX2NR1H4 | |
| SCHEMBL25530566 | 0.81 | CYP1A2 (0.41) | CYP1A2CYP2C19SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL25530554 | 0.81 | SLC6A4 (0.39) | CYP1A2CYP2C19RIPK1EPHX2NR1H4 | |
| SCHEMBL25530564 | 0.81 | CYP2C19 (0.44) | CYP1A2CYP2C19EPHX2NR1H4CYP2D6 | |
| SCHEMBL25530592 | 0.80 | CYP2C19 (0.50) | CYP1A2CYP2C19RIPK1EPHX2NR1H4 | |
| SCHEMBL20665206 | 0.80 | CYP2C19 (0.68) | CYP1A2CYP2C19RIPK1EPHX2NR1H4 | |
| SCHEMBL25530577 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2C19NR1H4CYP2D6HSP90AA1 | |
| SCHEMBL25530571 | 0.78 | CYP1A2 (0.39) | CYP1A2CYP2C19EPHX2NR1H4SLC6A4 | |
| SCHEMBL10162939 | 0.77 | EPHX2 (0.45) | CYP1A2CYP2C19RIPK1EPHX2NR1H4 | |
| SCHEMBL25587218 | 0.74 | CYP1A2 (0.42) | CYP1A2CYP2C19EPHX2NR1H4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | CYP1A2 3539/4885CYP2C19 2355/4885RIPK1 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.