Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530577 | 0.84 | CYP1A2 (0.41) | CYP1A2CYP2C19KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL25530560 | 0.83 | ADRA2A (0.39) | CYP1A2CYP2C19SLC6A4HTR2AKCNH2 | |
| SCHEMBL25536709 | 0.81 | CYP1A2 (0.37) | CYP1A2CYP2C19SLC6A4HTR2AKCNH2 | |
| SCHEMBL25574716 | 0.81 | CA1 (0.40) | CYP1A2CYP2C19KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL25530566 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2C19SLC6A4SLC6A2KDM4E | |
| SCHEMBL25530581 | 0.78 | CYP1A2 (0.44) | CYP1A2CYP2C19SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL25530564 | 0.75 | CYP2C19 (0.44) | CYP1A2CYP2C19KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL25530569 | 0.72 | HTR2A (0.37) | CYP1A2CYP2C19SLC6A4HTR2AKCNH2 | |
| SCHEMBL15803005 | 0.69 | KDM4E (0.40) | KDM4ECA1CA2CA9EPHX2 | |
| SCHEMBL10064792 | 0.69 | PDE2A (0.41) | KCNH2CA1CA2CA9EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | CYP1A2 3539/4885CYP2C19 2355/4885SLC6A4 3119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.