Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530657 | 0.81 | ROCK2 (0.38) | CYP4F2CYP4A11KDM4EALDH1A1MAPT | |
| SCHEMBL3124357 | 0.78 | LOXL2 (0.55) | CYP4F2CYP4A11KDM4EALDH1A1MAPT | |
| SCHEMBL12393362 | 0.73 | LOXL2 (0.48) | CYP4F2CYP4A11KDM4EALDH1A1MAPT | |
| SCHEMBL25530669 | 0.70 | AOC3 (0.36) | LOXL2MEP1BKMT2AMRGPRX4L3MBTL1 | |
| SCHEMBL4813988 | 0.70 | NR4A2 (0.49) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL165622 | 0.69 | LOXL2 (0.66) | CYP4F2CYP4A11KDM4EALDH1A1MAPT | |
| SCHEMBL31565671 | 0.68 | NR4A2 (0.47) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL697890 | 0.68 | LOXL2 (0.68) | CYP4F2CYP4A11KDM4EALDH1A1MAPT | |
| SCHEMBL31753372 | 0.66 | CYP4A11 (0.72) | CYP4F2CYP4A11KDM4EALDH1A1MAPT | |
| SCHEMBL28212 | 0.66 | LOXL2 (0.70) | CYP4F2CYP4A11KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093787-A1 | BENZODIAZEPINE COMPOUND AND APPLICATION THEREOF AS RHO KINASE INHIBITOR | 成都奥睿药业有限公司 | 2023-06-01 | — | — | WO | disclosed |