Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530952 | 0.94 | SIGMAR1 (0.61) | SIGMAR1HRH3KCNH2CACNA1IHRH1 | |
| SCHEMBL25530979 | 0.89 | SIGMAR1 (0.52) | SIGMAR1HRH3 | |
| SCHEMBL25530963 | 0.89 | SIGMAR1 (0.52) | SIGMAR1HRH3 | |
| SCHEMBL25530977 | 0.89 | SIGMAR1 (0.52) | SIGMAR1HRH3 | |
| SCHEMBL25530981 | 0.89 | SIGMAR1 (0.56) | SIGMAR1HRH3KCNH2CACNA1IL3MBTL1 | |
| SCHEMBL25531154 | 0.86 | SIGMAR1 (0.55) | SIGMAR1HRH3KCNH2CACNA1IHRH1 | |
| SCHEMBL23366631 | 0.86 | SIGMAR1 (0.74) | SIGMAR1HRH3KCNH2CACNA1IHRH1 | |
| SCHEMBL25531172 | 0.83 | SIGMAR1 (0.74) | SIGMAR1HRH3L3MBTL1 | |
| SCHEMBL25530974 | 0.83 | SIGMAR1 (0.74) | SIGMAR1HRH3L3MBTL1 | |
| SCHEMBL12666612 | 0.82 | SIGMAR1 (0.78) | SIGMAR1HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | SIGMAR1 1380/4885HRH3 2165/4885KCNH2 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.