Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.39 |
| ▸ | PGK2 | P07205 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 12/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483640 | 0.75 | FDPS (0.48) | LMNAFDPSBBOX1GGPS1 | |
| SCHEMBL5494372 | 0.75 | LMNA (0.39) | PGK1PGK2LMNAFDPSBBOX1 | |
| SCHEMBL23038652 | 0.73 | LMNA (0.43) | PGK1PGK2LMNAFDPSBBOX1 | |
| SCHEMBL15778355 | 0.71 | LMNA (0.36) | LMNAFDPSBBOX1GGPS1 | |
| SCHEMBL737339 | 0.71 | FDPS (0.40) | LMNAFDPSBBOX1GGPS1 | |
| SCHEMBL192295 | 0.70 | FDPS (0.38) | PGK1PGK2LMNAFDPSBBOX1 | |
| SCHEMBL23001089 | 0.68 | FDPS (0.45) | FDPSBBOX1LPAR1LPAR3GGPS1 | |
| SCHEMBL23001100 | 0.68 | FDPS (0.45) | FDPSBBOX1LPAR1LPAR3GGPS1 | |
| SCHEMBL1692406 | 0.68 | FDPS (0.52) | FDPSLPAR1LPAR3GGPS1 | |
| Hydrochloric Acid SCHEMBL17143219 | 0.68 | FDPS (0.37) | PGK1PGK2LMNAFDPSBBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210107942-A1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS INC (US) | 2021-04-15 | — | — | US | disclosed |
| US-10864253-B2 | Tissue protective peptides for preventing and treating diseases and disorders associated with tissue damage | ARAIM PHARMACEUTICALS, INC. (US) | 2020-12-15 | — | — | US | disclosed |
| US-20200360476-A1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. | 2020-11-19 | — | — | US | disclosed |
| US-20190134156-A1 | TISSUE PROTECTIVE PEPTIDES FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. | 2019-05-09 | — | — | US | disclosed |
| WO-2017189988-A1 | TISSUE PROTECTIVE PEPTIDES FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. (US) | 2017-11-02 | — | — | WO | disclosed |
| US-20170232066-A1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. | 2017-08-17 | — | — | US | disclosed |
| US-9580465-B2 | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage | ARAIM PHARMACEUTICALS, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160168199-A1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. | 2016-06-16 | — | — | US | disclosed |
| EP-2933264-A2 | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage | Araim Pharmaceuticals, Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| US-20150239932-A1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. | 2015-08-27 | — | — | US | disclosed |
| EP-2245056-B1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS INC (US) | 2015-03-11 | — | — | EP | disclosed |
| US-8853358-B2 | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage | ARAIM PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20110263504-A1 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. | 2011-10-27 | — | — | US | disclosed |
| EP-2245056-A2 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | Araim Pharmaceuticals, Inc. (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009094172-A2 | TISSUE PROTECTIVE PEPTIDES AND PEPTIDE ANALOGS FOR PREVENTING AND TREATING DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | ARAIM PHARMACEUTICALS, INC. (US) | 2009-07-30 | — | — | WO | disclosed |