Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494372 | 0.80 | LMNA (0.39) | FDPSLMNAPDE3AADRB3PDE4D | |
| SCHEMBL483640 | 0.75 | FDPS (0.48) | FDPSLMNAPDE3AADRB3PDE4D | |
| SCHEMBL23038652 | 0.73 | LMNA (0.43) | FDPSLMNAPDE3AADRB3PDE4D | |
| SCHEMBL15778355 | 0.71 | LMNA (0.36) | FDPSLMNAPDE3AADRB3PDE4D | |
| SCHEMBL2553124 | 0.71 | PGK1 (0.39) | FDPSLMNABBOX1GGPS1 | |
| SCHEMBL192295 | 0.70 | FDPS (0.38) | FDPSLMNABBOX1GGPS1 | |
| SCHEMBL1692406 | 0.68 | FDPS (0.52) | FDPSPDE3ASMPD1GGPS1 | |
| SCHEMBL23001089 | 0.68 | FDPS (0.45) | FDPSSMPD1BBOX1GGPS1 | |
| SCHEMBL23001100 | 0.68 | FDPS (0.45) | FDPSSMPD1BBOX1GGPS1 | |
| Hydrochloric Acid SCHEMBL17143219 | 0.68 | FDPS (0.37) | FDPSLMNABBOX1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138200-B2 | Compositions and methods for double-targeting virus infections and targeting cancer cells | WAKE FOREST UNIVERSITY (US) | 2012-03-20 | — | — | US | disclosed |
| US-20100184718-A1 | Compositions and Methods for Double-Targeting Virus Infections and Targeting Cancer Cells | WAKE FOREST UNIVERSITY | 2010-07-22 | — | — | US | disclosed |
| US-7638528-B2 | Compositions and methods for targeting cancer cells | WAKE FOREST UNIVERSITY SCHOOL OF MEDICINE (US) | 2009-12-29 | — | — | US | disclosed |
| US-7309696-B2 | Compositions and methods for targeting cancer cells | WAKE FOREST UNIVERSITY (US) | 2007-12-18 | — | — | US | disclosed |
| US-20060264397-A1 | Compositions and methods for targeting cancer cells | WAKE FOREST UNIVERSITY SCHOOL OF MEDICINE | 2006-11-23 | — | — | US | disclosed |
| US-7026469-B2 | Compositions and methods of double-targeting virus infections and cancer cells | WAKE FOREST UNIVERSITY SCHOOL OF MEDICINE (US) | 2006-04-11 | — | — | US | disclosed |
| EP-1389970-A4 | COMPOSITIONS AND METHODS OF DOUBLE-TARGETING VIRUS INFECTIONS AND CANCER CELLS | UNIV WAKE FOREST (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20040161398-A1 | Compositions and methods for targeting cancer cells | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2004-08-19 | — | — | US | disclosed |
| EP-1389970-A2 | COMPOSITIONS AND METHODS OF DOUBLE-TARGETING VIRUS INFECTIONS AND CANCER CELLS | WAKE FOREST UNIVERSITY (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6670341-B1 | Phosphocholine moiety covalently conjugated with one or more antiviral agents (e.g. nucleoside analogue, protease inhibitor, etc.) to a lipid backbone | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2003-12-30 | — | — | US | disclosed |
| WO-2002087465-A2 | COMPOSITIONS AND METHODS OF DOUBLE-TARGETING VIRUS INFECTIONS AND CANCER CELLS | WAKE FOREST UNIVERSITY (US) | 2002-11-07 | — | — | WO | disclosed |
| EP-1228080-A2 | COMPOSITIONS AND METHODS FOR DOUBLE-TARGETING VIRUS INFECTIONS AND TARGETING CANCER CELLS | WAKE FOREST UNIVERSITY (US) | 2002-08-07 | — | — | EP | disclosed |
| US-20020082242-A1 | Compositions and methods of double-targeting virus infections and cancer cells | WAKE FOREST UNIVERSITY SCHOOL OF MEDICINE | 2002-06-27 | — | — | US | disclosed |
| WO-2001034614-A2 | COMPOSITIONS AND METHODS FOR DOUBLE-TARGETING VIRUS INFECTIONS AND TARGETING CANCER CELLS | WAKE FOREST UNIVERSITY (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040161398-A1 | Compositions and methods for targeting cancer cells | PHOSPHO1, SGMS1, LPCAT1 | FDPS 2125/4885LMNA 857/4885PDE3A 2485/4885 |
| US-20060264397-A1 | Compositions and methods for targeting cancer cells | PHOSPHO1, SGMS1, LPCAT1 | FDPS 2125/4885LMNA 857/4885PDE3A 2485/4885 |
| US-20020082242-A1 | Compositions and methods of double-targeting virus infections and cancer cells | PHOSPHO1, PIGS, SMPD1 | FDPS 1483/4885LMNA 870/4885PDE3A 2653/4885 |
| US-20100184718-A1 | Compositions and Methods for Double-Targeting Virus Infections and Targeting Cancer Cells | PHOSPHO1, PIGS, SMPD1 | FDPS 2011/4885LMNA 734/4885PDE3A 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.