SCHEMBL25531850

SCHEMBL25531850

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)CN)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 1/20 0.41
▸ APLNR P35414 2/20 0.41
▸ RAMP3 O60896 10/20 0.39
▸ CALCR P30988 10/20 0.39
▸ NMUR2 Q9GZQ4 3/20 0.39
▸ NMUR1 Q9HB89 3/20 0.39
▸ REN P00797 1/20 0.37
▸ NTSR1 P30989 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018529 0.96 NAA50 (0.44) NAA50APLNRRAMP3CALCRNMUR2
SCHEMBL22018383 0.95 NAA50 (0.44) NAA50APLNRRAMP3CALCRNMUR2
SCHEMBL22018493 0.94 RAMP3 (0.43) NAA50APLNRRAMP3CALCR
SCHEMBL29308396 0.94 RAMP3 (0.43) NAA50APLNRRAMP3CALCR
SCHEMBL22018810 0.93 APLNR (0.48) NAA50APLNRRAMP3CALCRNMUR2
SCHEMBL22018502 0.93 APLNR (0.48) NAA50APLNRRAMP3CALCRNMUR2
SCHEMBL22018809 0.93 APLNR (0.48) NAA50APLNRRAMP3CALCRNMUR2
SCHEMBL22018340 0.93 APLNR (0.48) NAA50APLNRRAMP3CALCRNMUR2
SCHEMBL22018370 0.93 APLNR (0.48) NAA50APLNRRAMP3CALCRNMUR2
SCHEMBL22018380 0.93 APLNR (0.48) NAA50APLNRRAMP3CALCRNMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP NAA50 3485/4885APLNR 90/4885RAMP3 1263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback