Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22254829 | 0.91 | ROCK2 (0.40) | ROCK2MCHR1 | |
| SCHEMBL22249163 | 0.89 | ROCK2 (0.39) | ROCK2MCHR1KCNJ1KCNH2 | |
| SCHEMBL22248680 | 0.84 | ROCK2 (0.38) | ROCK2MCHR1KCNJ1KCNH2 | |
| SCHEMBL22254198 | 0.83 | ROCK2 (0.41) | ROCK2MCHR1 | |
| SCHEMBL22249169 | 0.83 | ROCK2 (0.44) | ROCK2MCHR1 | |
| SCHEMBL22254229 | 0.83 | ROCK2 (0.41) | ROCK2MCHR1 | |
| SCHEMBL22254235 | 0.83 | ROCK2 (0.41) | ROCK2MCHR1 | |
| SCHEMBL22248961 | 0.81 | ROCK2 (0.37) | ROCK2MCHR1 | |
| SCHEMBL22248952 | 0.80 | ROCK2 (0.36) | ROCK2MCHR1 | |
| SCHEMBL22248430 | 0.80 | ROCK2 (0.37) | ROCK2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | ROCK2 2850/4885MCHR1 4720/4885KCNJ1 1761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.