Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.70 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30364035 | 0.84 | CYP2B6 (0.88) | CYP2B6GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL19011533 | 0.84 | CYP2B6 (0.96) | CYP2B6GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL11398380 | 0.83 | CYP2B6 (1.00) | CYP2B6CHRM2CHRM1OPRM1KCNH2 | |
| SCHEMBL2697745 | 0.83 | CYP2B6 (1.00) | CYP2B6CHRM2CHRM1OPRM1KCNH2 | |
| SCHEMBL2697321 | 0.79 | CYP2B6 (0.66) | CYP2B6CHRM2CHRM1KCNH2ALDH1A1 | |
| SCHEMBL2696963 | 0.79 | CYP2B6 (0.66) | CYP2B6OPRM1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL3707837 | 0.78 | CYP2B6 (0.63) | CYP2B6GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL16079077 | 0.77 | CYP2B6 (0.58) | CYP2B6CHRM2CHRM1 | |
| SCHEMBL4669298 | 0.77 | OPRM1 (0.58) | CYP2B6CHRM2CHRM1OPRM1KCNH2 | |
| SCHEMBL6422796 | 0.77 | SIGMAR1 (0.62) | CYP2B6OPRM1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159593-A1 | CYCLOSPORINE ANALOGUES | UCL BUSINESS LTD (GB) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159593-A1 | CYCLOSPORINE ANALOGUES | HAVCR2, CHP1, HLA-C | CYP2B6 1012/4885GRIN2D 4833/4885GRIN3B 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.