Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.38 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23805939 | 0.89 | CYP2B6 (0.53) | CYP2B6SMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL12449606 | 0.84 | SIGMAR1 (0.50) | CYP2B6SMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL8354801 | 0.82 | CYP2B6 (0.44) | CYP2B6SMN1; SMN2LMNAGAAALDH1A1 | |
| SCHEMBL30364035 | 0.81 | CYP2B6 (0.88) | CYP2B6SMN1; SMN2LMNAALDH1A1OPRM1 | |
| SCHEMBL19011533 | 0.81 | CYP2B6 (0.96) | CYP2B6SMN1; SMN2LMNAOPRM1MEN1 | |
| SCHEMBL578326 | 0.81 | ALDH1A1 (0.44) | CYP2B6SMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL11541847 | 0.81 | SMN1; SMN2 (0.54) | CYP2B6SMN1; SMN2KCNA5LMNAGAA | |
| SCHEMBL10611 | 0.81 | CYP2B6 (0.43) | CYP2B6SMN1; SMN2LMNAALDH1A1HIF1A | |
| SCHEMBL11541844 | 0.81 | SMN1; SMN2 (0.54) | CYP2B6SMN1; SMN2KCNA5LMNAGAA | |
| SCHEMBL435727 | 0.79 | LMNA (0.48) | CYP2B6SMN1; SMN2KCNA5LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230129152-A1 | Compounds Comprising Perfluorinated Group, Photoinitiator Group, and Amide Linking Group | 3M INNOVATIVE PROPERTIES COMPANY | 2023-04-27 | — | — | US | disclosed |
| CN-114805727-A | Process for preparing molded flexible foams and flexible foams prepared therefrom | 科思创有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114773561-A | Process for producing molded flexible foam and flexible foam produced by the process | 科思创有限公司 | 2022-07-22 | — | — | CN | disclosed |
| US-8198299-B2 | Cycloalkylidene and heterocycloalkylidene inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20120045412-A1 | CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-02-23 | — | — | US | disclosed |
| US-8088771-B2 | Cycloalkylidene and heterocycloalkylidene inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100022543-A1 | CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2010-01-28 | — | — | US | disclosed |
| US-7560582-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-7560582-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| US-7247731-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-24 | — | — | US | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230129152-A1 | Compounds Comprising Perfluorinated Group, Photoinitiator Group, and Amide Linking Group | PFAS, AFF4, AFF1 | CYP2B6 905/4885SMN1; SMN2 3826/4885KCNA5 1573/4885 |
| US-20120045412-A1 | CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS | HDAC1, HDAC11, HDAC2 | CYP2B6 2859/4885SMN1; SMN2 3414/4885KCNA5 3821/4885 |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | THEM6, SOD1, SLC30A6 | CYP2B6 61/4885SMN1; SMN2 4366/4885KCNA5 1721/4885 |
| US-20100022543-A1 | CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS | HDAC1, HDAC11, HDAC2 | CYP2B6 2859/4885SMN1; SMN2 3414/4885KCNA5 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.