Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 7/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ozenoxacin SCHEMBL2553347 | 0.89 | TOP2A (0.43) | TOP2ATOP2BKCNH2 | |
| SCHEMBL5733690 | 0.88 | ADRB2 (0.43) | TOP2ATOP2BKCNH2ADRB2PIM1 | |
| Ozenoxacin SCHEMBL1711829 | 0.87 | TOP2A (0.45) | TOP2ATOP2BKCNH2 | |
| Ozenoxacin SCHEMBL29379004 | 0.87 | TOP2A (0.45) | TOP2ATOP2BKCNH2 | |
| Ozenoxacin SCHEMBL2551666 | 0.86 | TOP2A (0.45) | TOP2ATOP2BKCNH2 | |
| Ozenoxacin SCHEMBL2551660 | 0.86 | TOP2A (0.45) | TOP2ATOP2BKCNH2 | |
| Ozenoxacin SCHEMBL2550848 | 0.86 | TOP2A (0.45) | TOP2ATOP2BKCNH2 | |
| Ozenoxacin SCHEMBL2553340 | 0.86 | TOP2A (0.45) | TOP2ATOP2BKCNH2 | |
| Ozenoxacin SCHEMBL2553345 | 0.86 | TOP2A (0.45) | TOP2ATOP2BKCNH2 | |
| Ozenoxacin SCHEMBL2548603 | 0.85 | TOP2A (0.44) | TOP2ATOP2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556063-A1 | 1-CYCLOPROPYL-8-METHYL-7-[5-METHYL-6-(METHYLAMINO)-3-PYRIDINYL]-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID SALTS | Ferrer Internacional, S.A. (ES) | 2013-02-13 | — | — | EP | claimed |
| WO-2011124249-A1 | 1-CYCLOPROPYL-8-METHYL-7-[5-METHYL-6-(METHYLAMINO)-3-PYRIDINYL]-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID SALTS | FERRER INTERNACIONAL S.A. (ES) | 2011-10-13 | — | — | WO | claimed |
| US-8507684-B2 | 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid salts | FERRER INTERNACIONAL S.A. (ES) | 2013-08-13 | — | — | US | disclosed |
| US-20130040989-A1 | 1-CYCLOPROPYL-8-METHYL-7-[5-METHYL-6-(METHYLAMINO)-3-PYRIDINYL]-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID SALTS | FERRER INTERNACIONAL S.A. (ES) | 2013-02-14 | — | — | US | disclosed |
| EP-2556063-A1 | 1-CYCLOPROPYL-8-METHYL-7-[5-METHYL-6-(METHYLAMINO)-3-PYRIDINYL]-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID SALTS | Ferrer Internacional, S.A. (ES) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011124249-A1 | 1-CYCLOPROPYL-8-METHYL-7-[5-METHYL-6-(METHYLAMINO)-3-PYRIDINYL]-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID SALTS | FERRER INTERNACIONAL S.A. (ES) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040989-A1 | 1-CYCLOPROPYL-8-METHYL-7-[5-METHYL-6-(METHYLAMINO)-3-PYRIDINYL]-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID SALTS | FH, SLC25A11, HOGA1 | TOP2A 749/4885TOP2B 1454/4885KCNH2 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.