SCHEMBL25533541

SCHEMBL25533541

c1ccc(N(c2cccc(-c3cccc(-c4cccc5c4sc4ccccc45)c3)c2)c2ccccc2-c2cccc3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.45
PRKDC P78527 3/20 0.34
PARP14 Q460N5 1/20 0.33
MCL1 Q07820 2/20 0.33
ACMSD Q8TDX5 1/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
F9 P00740 1/20 0.33
CYP1A1 P04798 1/20 0.31
CYP1B1 Q16678 1/20 0.31
S1PR4 O95977 1/20 0.30
S1PR5 Q9H228 1/20 0.30
PIK3CD O00329 1/20 0.30
BRD4 O60885 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
MTOR P42345 1/20 0.30
PIK3CG P48736 1/20 0.30
KCNH2 Q12809 1/20 0.30
BRDT Q58F21 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25535817 0.98 ALOX5 (0.47) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25533533 0.98 ALOX5 (0.47) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25137812 0.97 ALOX5 (0.46) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25534067 0.97 ALOX5 (0.46) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25533916 0.97 ALOX5 (0.46) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25534363 0.97 ALOX5 (0.46) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25534837 0.96 ALOX5 (0.46) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25535815 0.95 ALOX5 (0.49) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25137668 0.95 ALOX5 (0.43) ALOX5PRKDCPARP14MCL1ACMSD
SCHEMBL25137654 0.95 ALOX5 (0.46) ALOX5PRKDCPARP14MCL1ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE LEF1, PIEZO1, ELAVL1 ALOX5 845/4885PRKDC 4598/4885PARP14 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.