Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22302453 | 0.85 | TYR (0.43) | TYRHSP90AA1HSP90AB1ERN1ALDH1A1 | |
| SCHEMBL12413853 | 0.84 | EIF4A3 (0.38) | TYRHSP90AA1HSP90AB1ERN1ALDH1A1 | |
| SCHEMBL29818615 | 0.83 | TYR (0.42) | TYRHSP90AA1HSP90AB1ERN1ALDH1A1 | |
| SCHEMBL13220718 | 0.77 | CA1 (0.39) | EIF4A3TSHRGABRA1GABRB2 | |
| SCHEMBL23257196 | 0.77 | ALDH1A1 (0.36) | TYRERN1ALDH1A1KDM4ETSHR | |
| SCHEMBL8830136 | 0.77 | TYR (0.43) | TYRHSP90AA1HSP90AB1ERN1ALDH1A1 | |
| SCHEMBL84113 | 0.77 | KDM4E (0.42) | TYRHSP90AA1HSP90AB1ERN1ALDH1A1 | |
| SCHEMBL18319085 | 0.75 | ALDH1A1 (0.35) | TYRERN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL650978 | 0.74 | ERN1 (0.50) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL11698528 | 0.74 | LMNA (0.39) | TYRHSP90AA1HSP90AB1ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159529-A1 | AROMATIC COMPOUND AND APPLICATION THEREOF IN ANTITUMOR DRUG | SHANGHAI ZHEYE BIOTECHNOLOGY CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159529-A1 | AROMATIC COMPOUND AND APPLICATION THEREOF IN ANTITUMOR DRUG | TYR, APC, TP53 | TYR 1/4885HSP90AA1 1546/4885HSP90AB1 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.