SCHEMBL25535941

SCHEMBL25535941

Cc1ccc(C)c(-c2ccc3c(-c4ccc(F)cc4)cccc3[n+]2C)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.38
GRM2 Q14416 1/20 0.37
S1PR4 O95977 3/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
RXFP1 Q9HBX9 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ALOX15 P16050 2/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ERAP1 Q9NZ08 1/20 0.32
SLC9A1 P19634 1/20 0.31
TLR8 Q9NR97 1/20 0.31
RIPK1 Q13546 1/20 0.31
CYP17A1 P05093 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26780765 0.81 CYP1A2 (0.43) ACHES1PR4HPGD
SCHEMBL25535780 0.78 ABL1 (0.33) ACHEGRM2NPC1RAB9AALOX15
SCHEMBL25535791 0.77 ABL1 (0.35) ACHEGRM2NPC1RAB9A
SCHEMBL26793196 0.75 S1PR4 (0.35) S1PR4MAPTMEN1KMT2A
SCHEMBL26793530 0.75 S1PR4 (0.32) S1PR4
SCHEMBL26780887 0.75 TERT (0.33)
SCHEMBL25534898 0.73 NR1H2 (0.34) GRM2NPC1RAB9ASMN1; SMN2CYP17A1
SCHEMBL27887044 0.72 ACHE (0.50) ACHEGRM2NPC1RAB9ARXFP1
SCHEMBL26781079 0.72
SCHEMBL26780884 0.71 TERT (0.33) S1PR4RXFP1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157153-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed