Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | GYS1 | P13807 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25534895 | 0.87 | MAPK14 (0.38) | CYP17A1GRM2TNKSMAPK14TNKS2 | |
| SCHEMBL25534899 | 0.86 | NR1H2 (0.32) | NR1H2NR1H3CYP17A1GRM2RAB9A | |
| SCHEMBL25534886 | 0.84 | NR4A2 (0.37) | GRM2TSHRMAPK14GCGRHMGCR | |
| SCHEMBL25535510 | 0.80 | TNKS2 (0.35) | GRM2TSHRTNKS2HMGCRRAB9A | |
| SCHEMBL26257955 | 0.78 | KIF11 (0.35) | TP53 | |
| SCHEMBL25494061 | 0.75 | CYP1A2 (0.39) | TSHR | |
| SCHEMBL25518414 | 0.74 | CYP2A6 (0.40) | TSHR | |
| SCHEMBL27887044 | 0.73 | ACHE (0.50) | GRM2MAPK14GCGRRAB9ANPC1 | |
| SCHEMBL25535941 | 0.73 | ACHE (0.38) | CYP17A1GRM2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25534884 | 0.72 | PTGS2 (0.41) | CYP17A1TSHRTNKSMAPK14TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230157153-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-05-18 | — | — | US | disclosed |