SCHEMBL25536003

SCHEMBL25536003

c1cc(-c2ccc3c(c2)sc2ccccc23)cc(N(c2ccccc2-c2ccc3ccccc3c2)c2ccccc2-c2cccc3c2sc2ccccc23)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
S1PR5 Q9H228 9/20 0.35
S1PR4 O95977 7/20 0.35
PRKDC P78527 3/20 0.34
PARP14 Q460N5 1/20 0.33
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
LIMK1 P53667 1/20 0.30
PIK3CD O00329 1/20 0.30
BRD4 O60885 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
MTOR P42345 1/20 0.30
PIK3CG P48736 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25535972 0.96 ALOX5 (0.45) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25558324 0.96 ALOX5 (0.41) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25535965 0.96 ALOX5 (0.46) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25535424 0.95 ALOX5 (0.46) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25536256 0.95 ALOX5 (0.46) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25536260 0.94 ALOX5 (0.45) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25536000 0.94 ALOX5 (0.42) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25535429 0.94 ALOX5 (0.45) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25536005 0.94 ALOX5 (0.46) ALOX5S1PR5S1PR4PRKDCPARP14
SCHEMBL25535968 0.94 S1PR5 (0.38) ALOX5S1PR5S1PR4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172058-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE LEF1, PIEZO1, ELAVL1 ALOX5 845/4885S1PR5 4533/4885S1PR4 3989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.