Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.54 |
| ▸ | SKP1 | P63208 | 1/20 | 0.54 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462705 | 0.87 | CKS1B (0.53) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL6502339 | 0.86 | KCNA3 (0.53) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL6503772 | 0.82 | CKS1B (0.48) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL6503768 | 0.82 | CKS1B (0.48) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL24292130 | 0.82 | KCNA3 (0.49) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL17830852 | 0.81 | CKS1B (0.61) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL1271996 | 0.81 | CKS1B (0.55) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL6223295 | 0.80 | CKS1B (0.46) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL19284706 | 0.80 | CKS1B (0.57) | CKS1BSKP1SKP2KCNA3PIM1 | |
| SCHEMBL20133857 | 0.80 | DRD2 (0.60) | CKS1BSKP1SKP2KCNA3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |