SCHEMBL25536162

SCHEMBL25536162

Cc1cc(C)c(C)c(-c2cc3ccc(-c4ccc(F)cc4)cc3c[n+]2C)c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.33
PGR P06401 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
ALDH1A3 P47895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25536160 0.87 ABL1 (0.38) ABL1PGR
SCHEMBL25518735 0.85 FFAR4 (0.31) FFAR4
SCHEMBL25536079 0.83 PGR (0.41) ABL1PGRKDM4EALDH1A1
SCHEMBL25536169 0.82 ABL1 (0.35) ABL1PGRKDM4ETNKS2
SCHEMBL25535793 0.79 ACHE (0.32) ABL1PGRKDM4EALDH1A1TNKS2
SCHEMBL25535783 0.79 PGR (0.32) ABL1PGRKDM4EALDH1A1TNKS2
SCHEMBL25518640 0.79 CYP2A6 (0.38)
SCHEMBL25776478 0.78 SLC6A2 (0.30)
SCHEMBL25518663 0.77 CYP2A6 (0.39) KDM4EALDH1A1
SCHEMBL26836349 0.77 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157153-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed