Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472026 | 0.89 | CTSV (0.41) | CTSBCYP19A1MAPTLMNANPC1 | |
| SCHEMBL2558223 | 0.85 | CNR1 (0.40) | CNR1CNR2GPR84HCKMAPK12 | |
| SCHEMBL12634044 | 0.84 | CYP11B1 (0.47) | CYP11B1CYP11B2CTSBCYP19A1MAPT | |
| SCHEMBL535781 | 0.83 | MAPT (0.44) | CTSBMAPTLMNANPC1RAB9A | |
| SCHEMBL2572968 | 0.80 | HCK (0.52) | CYP11B1CYP11B2CYP19A1MAPTLMNA | |
| SCHEMBL1978086 | 0.80 | MAPK14 (0.48) | CYP11B1CYP11B2CYP19A1LMNANPC1 | |
| SCHEMBL1978082 | 0.80 | MAPK14 (0.48) | CYP11B1CYP11B2CYP19A1LMNANPC1 | |
| SCHEMBL2473217 | 0.77 | MAPT (0.43) | CTSBMAPTLMNANPC1RAB9A | |
| SCHEMBL2405629 | 0.76 | MAPK14 (0.48) | CYP11B1CYP11B2LMNANPC1RAB9A | |
| SCHEMBL2548864 | 0.75 | HCK (0.43) | CYP11B1CYP11B2MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556067-A2 | PYRAZOLYL UREAS AS P38 MAP KINASE INHIBITORS | Respivert Limited (GB) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011124923-A2 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2011-10-13 | — | — | WO | disclosed |