Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 15/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19347388 | 0.91 | PHGDH (0.47) | PHGDHTP53RXFP1LMNA | |
| SCHEMBL26326966 | 0.91 | PHGDH (0.45) | PHGDHTP53RXFP1LMNA | |
| SCHEMBL25536653 | 0.86 | PHGDH (0.51) | PHGDHTP53RXFP1LMNA | |
| SCHEMBL20794390 | 0.86 | PHGDH (0.63) | PHGDH | |
| SCHEMBL24208289 | 0.78 | PHGDH (0.59) | PHGDH | |
| SCHEMBL25536757 | 0.77 | PHGDH (0.57) | PHGDH | |
| SCHEMBL19347375 | 0.77 | PHGDH (0.58) | PHGDH | |
| SCHEMBL30637859 | 0.77 | PHGDH (0.58) | PHGDH | |
| SCHEMBL20768586 | 0.76 | PHGDH (0.58) | PHGDH | |
| SCHEMBL20768585 | 0.76 | PHGDH (0.58) | PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426244-B1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS INC (US) | 2023-06-07 | — | — | EP | disclosed |