SCHEMBL25536748

SCHEMBL25536748

CC1(C)c2cccc(-c3ccc(-c4cc(-c5ccc6sc7ccccc7c6c5)nc(-c5ccccc5)n4)c4ccccc34)c2-c2ccc3ccccc3c21

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
PIM1 P11309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25536746 0.94 F9 (0.32) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL25539162 0.94 PIM1 (0.31) PIM1
SCHEMBL25536626 0.91 KDM4E (0.31) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL25537138 0.91 KDM4E (0.31) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL25534082 0.91 MEN1 (0.33) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL25536745 0.90 ALOX5 (0.35) KDM4EALDH1A1MAPTHPGD
SCHEMBL25537310 0.90 MEN1 (0.34) KDM4EMEN1ALDH1A1LMNAGLA
SCHEMBL25537787 0.89 F9 (0.31) KDM4EALDH1A1MAPTHPGD
SCHEMBL25536750 0.89 F9 (0.31) KDM4EALDH1A1MAPTHPGD
SCHEMBL25536767 0.89 MEN1 (0.34) KDM4EMEN1ALDH1A1LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167072-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM KDM4E 1565/4885MEN1 267/4885ALDH1A1 254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.